Predictors of Adherence with Positive Airway Pressure Treatment in Patients with Obstructive Sleep Apnea in Korean

Kim, Myung Jin; Kim, Min Jae; Bae, Sung Hee; Park, Chan Hum; Kim, Dong Kyu

doi:2015.22.2.89

J Rhinol > Volume 22(2); 2015

Original Article

Journal of Rhinology 2015;22(2):89-95.
Published online November 30, 2015.
DOI: https://doi.org/10.18787/jr.2015.22.2.89

Predictors of Adherence with Positive Airway Pressure Treatment in Patients with Obstructive Sleep Apnea in Korean

Myung Jin Kim, Min Jae Kim, Sung Hee Bae, Chan Hum Park, Dong Kyu Kim

¹Department of Otorhinolaryngology-Head Neck Surgery, Chuncheon Sacred Heart Hospital, Chuncheon, Korea. doctordk@naver.com
²Nano-Bio Regenerative Medical Institute, College of Medicine, Hallym University, Chuncheon, Korea.

폐쇄성 수면 무호흡증후군 환자에서 자동형 양압 호흡기 치료의 순응도 예측인자 분석

김명진, 김민재, 배승희, 박찬흠, 김동규

한림대학교 의과대학 춘천성심병원 이비인후-두경부외과학교실,¹ 나노 바이오 재생의학연구소²

Abstract

Background and Objectives
Application of automatic positive airway pressure (APAP) is regarded as the primary therapy for patients with obstructive sleep apnea syndrome (OSAS). However, a low adherence rate is a major problem with APAP treatment in OSAS patients. Therefore, the aim of the present study is to assess factors related to good adherence of APAP therapy in OSAS Korean patients.
Materials and Method
Of 112 consecutive newly diagnosed moderate to severe OSAS patients, 70 were enrolled in this study. All patients received APAP therapy for 2 weeks, along with reinforcing intervention, consisting of motivational reinforcement and technical support. All APAP therapy involved a device rental service. After 2 weeks of treatment, patients had to choose the kind of treatment for OSAS [APAP therapy (good adherence) or alternative treatment options (poor adherence)].
Results
After 6 months, the adherence rate to APAP therapy was 35.7% (n=25). No statistically significant difference was observed between the good and poor adherence groups with regard to snoring intensity, apnea-hypopnea index, and mean O2 saturation after adjusting for age, sex, body mass index, marital status, and socioeconomic status. However, we found that excessive daytime sleepiness and lowest O2 saturation were significantly associated with good adherence [adjusted odds ratios (ORs)=9.515 and 2.327] after adjusting for age, sex, body mass index, marital status, and socioeconomic status.
Conclusion
Our findings suggest that excessive daytime sleepiness and lowest O2 saturation are important factors to identify good adherence to APAP treatment in Korean OSAS patients.

Key Words: Obstructive sleep apnea syndrome;Automatic positive airway pressure;Adherence