Journal of Rhinology 2010;17(1):24-28.
Published online May 31, 2010.
The Effect of the Combined Use of Immunotherapy and Topical Steroid on the Quality of Life in Allergic Rhinitis Patients
Seok Chan Hong, Yong Soo Jeong, Jin Kook Kim, Jae Hoon Cho, Hong Ju Park
Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Seoul, Korea.
면역요법과 국소용 스테로이드제 분무의 병용요법이 알레르기비염 환자의 삶의 질에 미치는 영향
홍석찬, 정용수, 김진국, 조재훈, 박홍주
건국대학교 의학전문대학원 이비인후-두경부외과학교실
Background and Objectives
The management of allergic rhinitis includes allergen avoidance, pharmacotherapy, and immunotherapy. Only a few studies have compared the clinical efficacy of the two treatments. We conducted a study to compare the efficacy of immunotherapy (IT), a topical steroid (TS), and combined therapy (IT+TS) in allergic rhinitis.
Materials and Method
S: The three groups (IT:11 patients, TS:ten patients, IT+TS:ten patients) were treated for six months and were evaluated using questionnaires and a physical exam before and after treatment. RESULT: Overall symptoms were reduced after six months of treatment in all groups. In the IT+TS group, signs and symptoms diminished more than those in the IT or TS groups. Difference in skin test sensitivity among the groups was not statistically significant.
Combined use of immunotherapy and a topical steroid was more effective than either therapy alone in reducing the signs and symptoms of allergic rhinitis.
Key Words: Allergic rhinitis;Immunotherapy;Topical steroid

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