The Impact of Nasal Polyposis on Olfactory Dysfunction in Chronic Rhinosinusitis

Yoon, Hee Chul; Kim, Tae Min; Joo, Jae Woo; Song, In Sik; Hong, Seung No; Yoo, Joon Hyuk; Lee, Seung Hoon

doi:2017.24.1.31

J Rhinol > Volume 24(1); 2017

Original Article

Journal of Rhinology 2017;24(1):31-36.
Published online May 31, 2017.
DOI: https://doi.org/10.18787/jr.2017.24.1.31

The Impact of Nasal Polyposis on Olfactory Dysfunction in Chronic Rhinosinusitis

Hee Chul Yoon, Tae Min Kim, Jae Woo Joo, In Sik Song, Seung No Hong, Joon Hyuk Yoo, Seung Hoon Lee

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University Ansan Hospital, Ansan, Korea. shleeent@korea.ac.kr

만성 비부비동염 환자에서의 비용이 후각장애에 주는 영향

윤희철, 김태민, 주재우, 송인식, 홍승노, 유준혁, 이승훈

고려대학교 의과대학 안산병원 이비인후-두경부외과학교실

Abstract

Background and Objectives
Olfactory disturbance is a major sinonasal symptom of chronic rhinosinusitis (CRS) with nasal polyps (NP). The aim of this study was to investigate the relationship between the severity of nasal polyposis and olfactory dysfunction in CRS.
SUBJECTS AND METHOD
A total of 277 subjects with CRS were included in this study. All participants were divided into four groups according to the size and degree of the nasal polyposis: the control group (no polyp; n=79); NP (nasal polyp) group I (both or unilateral simple polyposis; n=85); NP group II (unilateral diffuse polyposis; n=66); and NP group III (bilateral diffuse polyposis; n=47). We analyzed the relationships between the severity of nasal polyposis and olfactory dysfunction using both the Korean Version of the “Sniffin'Sticks” test (KVSS Test) II and the Questionnaire of Olfactory Disorders (QOD).
Results
The KVSS Test II TDI score was significantly decreased in the bilateral diffuse polyposis group (NP group III=15.62±13.39) compared to the other polyp groups [control group=25.04±9.67 (p<0.001); NP group I=21.67±11.18 (p=0.005); NP group II=21.51±10.85 (p=0.008)]. However, there were no significant differences in the KVSS Test II TDI score between the control group and NP groups I and II. For the QOD_NS score, only NP group III (11.51±9.87) had significantly increased values compared to the control group [8.42±12.27 (p=0.015)].
Conclusion
These results suggest that bilateral diffuse nasal polyposis is related to significant olfactory dysfunction in CRS.

Key Words: Nasal polyp;Rhinosinusitis;Olfaction