A Case of Rhino-Orbito-Cerebral Mucormycosis

Lee, Kyung Chul; Hong, Seok Jin; Kim, Tae Hyung; Kang, Il Gyu

Case Report

Journal of Rhinology 2003;10(Suppl DB Error: syntax error):49-52.
Published online November 30, 2003.

A Case of Rhino-Orbito-Cerebral Mucormycosis

Kyung Chul Lee, Seok Jin Hong, Tae Hyung Kim, Il Gyu Kang

Department of Otolaryngology Head and Neck Surgery, College of Medicine, Sungkyunkwan University, Kangbuk Samsung Medical Center, Seoul, Koreafess@samsung.co.kr

Abstract

Rhino-orbito-cerebral mucormycosis is a rare opportunistic invasive fungal infection, with rapid progression and high mortality. It is characterized by an aggressive necrotizing infection spreading from the nose to the paranasal sinuses, orbit, and the brain. This disease is often associated with diabetic ketoacidosis, leukemia, malnutrition, AIDS and immunocompromis ed patients. Typical initial symptoms of a patient with rhino-orbito-cerebral mucormycosis are facial pain and swelling, headache, fever, and blood-tinged rhinorrhea. Symptoms rapidly progressed to facial or orbital cellulitis, proptosis, and visual loss, facial nerve palsy. We report a case report of a 66-year-old woman with poorly controlled diabetes mellitus who developed mucormycosis which involved unilateral paranasal sinus, orbit, and selective cranial nerves.

Key Words: Mucormycosis;Nose;Orbit;Cranial nerves