J Rhinol > Volume 23(1); 2016
Journal of Rhinology 2016;23(1):24-30.
Published online May 31, 2016.
DOI: https://doi.org/10.18787/jr.2016.23.1.24   
Correlation Between Salivary Alpha-Amylase Level and Heart Rate Variability in Pediatric Subjects with Sleep-Disordered Breathing
Se Hwan Hwang, Heung Ku Lee, Rae Hyung Kim, Soo Hyung Lee, Gibeom Ko, Chan Soon Park
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. pcs0112@catholic.ac.kr
수면호흡장애가 있는 소아의 타액 알파 아밀라아제 수준과 심박동률 변이도 간 상관관계
황세환, 이흥구, 김래형, 이수형, 고기범, 박찬순
가톨릭대학교 의과대학 이비인후-두경부외과학교실
Abstract
Background and Objectives
The aim of this study was to evaluate the relationship between salivary alpha-amylase (sAA) and heart rate variability (HRV) indices in SDB children based on objective parameters of polysomnography (PSG).
Materials and Method
This prospective study enrolled 67 children who underwent a physical examination and full-attended in-lab PSG with continuous electrocardiographic signal. The sAA were measured at night before PSG and in the early morning after PSG.
Results
The subjects were divided into control [n=26, apnea-hypopnea index (AHI)≤1] and obstructive sleep apnea syndrome (OSAS, n=41, AHI>1) groups; the OSAS group was subdivided into mild (1Conclusion
TAlthough both HRV and sAA were useful methods of predicting severe OSAS in children, a weak correlation between HRV and sAA was shown in pediatric OSAS subjects. Therefore, HRV and sAA may be independent parameters revealing different aspects of pediatric OSAS.
Key Words: Child;Heart rate;Saliva;Alpha-Amylases;Sleep apnea syndromes;Correlation;Polysomnography




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