Sinonasal Undifferentiated Pleomorphic Sarcoma in Five Patient Cases

Kim, Sung Hee; Kim, Min Joo; Lee, Bong Jae; Kim, Ji Heui

doi:2016.23.2.115

J Rhinol > Volume 23(2); 2016

Case Report

Journal of Rhinology 2016;23(2):115-118.
Published online November 30, 2016.
DOI: https://doi.org/10.18787/jr.2016.23.2.115

Sinonasal Undifferentiated Pleomorphic Sarcoma in Five Patient Cases

Sung Hee Kim, Min Joo Kim, Bong Jae Lee, Ji Heui Kim

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jhkim0217@gmail.com

Abstract

Undifferentiated pleomorphic sarcoma (UPS) is a rare soft tissue sarcoma of the sinonasal area. Here, we present two primary cases of UPS and three post-irradiation sinonasal UPS cases. Imaging findings were misinterpreted by radiologists as representing other malignant tumors or recurrence of the primary tumor. Our cases indicate that post-irradiation UPS can originate within any part of the radiation field. Treatment outcomes of primary sinonasal UPS seem to be favorable if the tumor is treated aggressively, but the outcomes of post-irradiation sinonasal UPS may be poor if appropriate surgical margins cannot be obtained.

Key Words: Undifferentiated pleomorphic sarcoma;Paranasal sinus;Nasal cavity;Radiation