J Rhinol > Epub ahead of print
Published online January 15, 2021.
DOI: https://doi.org/10.18787/jr.2020.00342    [Epub ahead of print]
Late Metastatic Renal Cell Carcinoma Recurrence Presenting as a Maxillary Sinus Mass 12 Years after Nephrectomy: Case Report and Literature Review
Yeon-Hee Joo1,3, Yung Jin Jeon2, Hyun-Jin Cho2, Sang-Wook Kim2,3
1Department of Otorhinolaryngology, Gyeongsang National University Changwon Hospital and Gyeongsang National University College of Medicine, Changwon, Korea
2Department of Otorhinolaryngology, Gyeongsang National University Hospital and Gyeongsang National University College of Medicine, Jinju, Korea
3Institute of Health Sciences, Gyeongsang National University, Jinju, Korea
Correspondence: 
Yeon-Hee Joo, Tel: +82-55-214-3863, Fax: +82-55-214-3262, Email: yhjoo@gnuh.co.kr
Received: 26 October 2020   • Revised: 24 December 2020   • Accepted: 24 December 2020
Abstract
Metastasis to the sinonasal cavity is rare. Late recurrence, such as metastasis developing 10 years or more after nephrectomy, is even more rare. We present a rare case of late metastatic renal cell carcinoma (RCC) in the maxillary sinus after nephrectomy and discuss reported sinonasal metastatic RCC cases. A 64-year-old man presented with left nasal obstruction for the previous one year. He had undergone right nephrectomy to treat RCC 12 years prior. Paranasal sinus computed tomography and magnetic resolution imaging revealed a 4.6-cm-diameter mass exhibiting delayed contrast enhancement that filled the left maxillary sinus and the nasal cavity. Histologically, clear cell RCC was diagnosed. We resected the maxillary sinus tumor to resolve the nasal obstruction for palliative symptom relief. There has been no evidence of recurrence to date, 3 years postoperatively. When a patient with a history of RCC presents with a hypervascular paranasal sinus mass, metastatic RCC should be considered, despite history of nephrectomy. It is important to make an appropriate treatment plan depending on extent of metastases and location of the metastatic tumor.
Key Words: Renal cell carcinomaMetastasisParanasal sinusNephrectomy


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