| The Effects of Olfactory Training with Intranasal Corticosteroid Spray in Korean Patients with Olfactory Dysfunction |
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Young Do Jung, Deok Su Kim, Byung Jun Kang, Seung Heon Shin, Mi Kyung Ye |
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Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu, Daegu, Korea. miky@cu.ac.kr |
| 한국인 후각장애환자에서 후각훈련과 비강내 스테로이드 스프레이의 효과 |
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정영도, 김덕수, 강병준, 신승헌, 예미경 |
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대구가톨릭대학교 의과대학 이비인후과학교실 |
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| Abstract |
Background and Objectives
Olfactory training is an alternative treatment based on modulation of the regeneration process of the olfactory system via repeated exposure to odors. Our study aimed to investigate the impact of olfactory training with intranasal corticosteroid in Korean patients with various causes of olfactory dysfunction.
SUBJECTS AND METHOD
Our study population comprised 134 adults with olfactory dysfunction of different etiologies (postviral infection n=85; post-traumatic n=18; and idiopathic n=31). For training, patients exposed themselves to four different odors twice a day. All patients used fluticasone nasal spray (two sprays in each nostril once daily). Olfactory function was evaluated at baseline and again at three months, and results were quantified as patient TDI (threshold, discrimination, and identification) score RESULTS: Olfactory function improved in 74 of 134 patients (55.2%). Etiology of olfactory disorder, sex, and age had statistically significant influence on the improvement rate of olfactory function, among which etiology of olfactory loss was the most important. However, initial severity and duration of olfactory loss had no statistically significant influence on the improvement rate. The TDI score at three months of olfactory training showed remarkable improvement, primarily because of improvements in the discrimination and identification components.
Conclusion
The present study showed that olfactory training with intranasal corticosteroid was beneficial to improve olfactory function in patients with olfactory dysfunction, particularly in postviral infection patients. |
| Key Words:
Olfaction disorders;Postviral;Post-traumatic;Olfactory training |
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