Primitive Neuroectodermal Tumor of Nasal Cavity: Case Report

Lee, Heung Man; Han, Seung Hoon; Woo, Jeong Su; Cho, Seong Jin; Kim, Han Kyeom; Lee, Sang Hag

Case Report

Journal of Rhinology 1997;4(1):57-60.
Published online May 31, 1997.

Primitive Neuroectodermal Tumor of Nasal Cavity: Case Report

Heung Man Lee, Seung Hoon Han, Jeong Su Woo, Seong Jin Cho, Han Kyeom Kim, Sang Hag Lee

¹Department of Otorhinolaryngology- Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
²Department of Surgical Pathology, Korea University College of Medicine, Seoul, Korea.

Abstract

The primitive neuroectodermal tumor is a highly malignant small round cell tumor characterized by neuroectodermal origin and poor prognosis. The thoracopulmonary region is known to be the most common site of the disease, with peak incidence during adolescence. Primitive neuroectodermal tumors are very rarely reported in the head and neck area, and there have been only a few involving the nasal cavity. We treated a 60 year-old female patient who had nasal obstruction over a three-month period with radical surgery and postoperative radiation therapy. This paper presents our diagnostic workup and approach in treating this unique tumor, and the immunohistochemical findings. A guideline for the treatment of this aggressive neoplasm is reviewed with our experiences in treating this primitive neuroectodermal tumor of the nasal cavity by combined treatment modalities.

Key Words: Primitive neuroectodermal tumor;Nasal cavity