J Rhinol > Volume 24(2); 2017
Journal of Rhinology 2017;24(2):89-93.
Published online November 30, 2017.
DOI: https://doi.org/10.18787/jr.2017.24.2.89   
Difference according to Interpretation Methods in Allergic Skin Test
Sung Hwa Dong, Su Young Jung, Jin Young Min, Su Jin Kim, Kun Hee Lee, Joong Saeng Cho, Sung Wan Kim
1Department of Otorhinolaryngology-Head and Neck Surgery, Kyung Hee University, Graduate School, Seoul, Korea. drkimsw@hanmail.net
2Department of Otorhinolaryngology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
알레르기 피부반응 검사 결과의 판독 방법에 따른 차이
동성화, 정수영, 민진영, 김수진, 이건희, 조중생, 김성완
경희대학교 의과대학 이비인후-두경부외과학교실,1 을지대학교 을지병원 이비인후과학교실2
Abstract
Background and Objectives
The skin prick test is a widely used test that uses three methods (allergen/histamine ratio method, erythema size method, and wheal size method) to interpret the results. However, there has been no comparison of these methods. The aim of this study is to compare the three different interpretation methods and define the relationship among them.
SUBJECTS AND METHOD
A total of 139 patients who visited our allergy clinic complaining of nasal symptoms were enrolled. Three interpretation methods were used for defining positivity in the skin prick test, and their results were compared. The validity of each interpretation method was evaluated by total nasal symptom score.
Results
Positivity in the skin prick test was reported in 48.2% of patients according to the allergen/histamine ratio method and in 64.0% of patients according to the wheal size method and erythema size method. The proportion of subjects who showed a negative result with the allergen/histamine ratio method but positive results with the wheal size method or erythema size method was 15.8%. This group had a significantly higher total nasal symptom score, especially rhinorrhea and nasal obstruction, than subjects who showed negative results on all three methods.
Conclusion
When diagnosing allergic rhinitis patients using the skin prick test, the wheal size method and erythema size method should be considered rather than the allergen/histamine ratio method.
Key Words: Diagnosis;Skin test;Allergic rhinitis


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