Journal of Rhinology 2001;8(Suppl DB Error: syntax error):58-62.
Published online May 31, 2001.
The Effect of Capsaicin Spray in Nasal Hyperreactivity
Tae Young Jang, Seung Yoeung Song, Tae Man Kim
1Department of Otorhinolaryngology, College of Medicine, InHa University, Incheon, Korea.
2Department of Otolaryngology, Incheon Christian Hospital, Incheon, Korea.
Capsaicin, a nonenamide derived from Capsicum plants, has proven to be useful in patients with vasomotor rhintitis. In this study, we estimated the effects of 10-5 M capsaicin spray in patients with hypersensitive rhinitis. The drug was given 3 times per day for 3 days to each patient by means of a spray delivered to the nasal mucosa. Patient's symptom score was recorded by the same physician. We repeated this method after 1 week, 2 week, 4week, 8week, 12week, 16week and recorded their symptom score. As a result, the mean symptom score involving nasal obstruction, sneezing, rhinorrhea and itching was remarkably reduced by capsaicin spray. The present findings suggest that capsacine spray is a good therpheutic method for hypersensitive rhinitis patients.
Key Words: Capsaicin;Hypersensitive rhinitis

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