Comparison of Clinical Characteristics of B Cell Lymphoma and NK/T cell Lymphoma of the Nose and Paranasal Sinuses |
Kwang Woo Han, Se Jun Choi, Ki Hoon Pae, Yoo Sam Chung, Yong Ju Jang, Bong Jae Lee |
Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. bjlee@amc.seoul.kr |
비강 및 부비동에 발생한 NK/T세포 림프종과 B세포 림프종의 임상적 특징 비교 |
한광우, 최세준, 배기훈, 정유삼, 장용주, 이봉재 |
울산대학교 의과대학 서울아산병원 이비인후과학교실 |
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Abstract |
Background and Objectives There are various subtypes in lymphoma of the nasal cavity and paranasal sinuses. This study aimed to compare the clinical differences between NK/T cell lymphoma and B cell lymphoma in the nose and paranasal sinuses. MATERIALS AND METHODS From 1991 through 2003, 18 patients were diagnosed with lymphoma by histopathologic biopsy (NK/T cell 13 : B cell 5). We reviewed the medical records retrospectively regarding subjective symptoms, physical findings, and PNS CT findings. Results The most common symptom of NK/T cell lymphoma was nasal obstruction (8/13), and the main endoscopic finding was ulcerative small lesion. The PNS CT finding of NK/T cell lymphoma was homogenous, poorly enhanced, small mass. In contrast, the most common symptom of B cell lymphoma was periorbital swelling (2/5), and the main endoscopic finding was fungating mass. The PNS CT finding of B cell lymphoma was heterogenous, well-enhanced, large mass with bone destruction. The location of NK/T cell lymphoma was the inferior or middle turbinate in the nasal cavity, whereas the location of B cell lymphoma was the ethmoid or maxillary sinus. Conclusion It is suggested that there may be significant clinical differences between NK/T cell lymphoma and B cell lymphoma in the sinonasal cavity. |
Key Words:
Paranasal sinus neoplasms;Nose neoplasms;B cell lymphoma |
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