A Case of Intranasal Pleomorphic Adenoma Arising from the Nasal Septum and Clivus

Park, Chan Soon; Jung, Ji Han; Bae, Seong Cheon; Park, Yong Jin

Case Report

Journal of Rhinology 2006;13(1):45-48.
Published online May 31, 2006.

A Case of Intranasal Pleomorphic Adenoma Arising from the Nasal Septum and Clivus

Chan Soon Park, Ji Han Jung, Seong Cheon Bae, Yong Jin Park

¹Department of Otolaryngology-HNS, Collage of Medicine, The Catholic University of Korea, Seoul, Korea. yp@catholic.ac.kr
²Department of Clinical Pathology, Collage of Medicine, The Catholic University of Korea, Seoul, Korea.

비중격과 경사대에서 발생한 비내 다형성 선종 1예

박찬순, 정지한, 배성천, 박용진

가톨릭대학교 의과대학 이비인후과학교실,¹ 임상병리학교실²

Abstract

Pleomorphic adenomas arise most commonly in the major salivary glands. It has rarely been described arising in the nasal cavity. A 65-year-old woman presented with a 9-month-history of left sided nasal obstruction. Endoscopic examination and computed tomographic scan revealed a lobulated tumor mass arising from the left bony nasal septum and clivus. It was removed endoscopically with endonasal approach. Histologic examination showed a lobular and duct-like structures consisting of a loose myxoid stoma consistent with characteristics of a pleomorphic adenoma. There was positive immunohistochemical expression of cytokeratin and S-100 protein which confirmed earlier histopathological diagnosis. We report a very rare case of pleomorphic adenoma originating from the nasal septum and clivus with a review of literature.

Key Words: Pleomorphic adenoma;Nasal cavity