| Bacteriological Findings and Antimicrobial Susceptibility in Chronic Sinusitis with Nasal Polyp |
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Hyun Jun Kim, Kyungwon Lee, Jong Bum Yoo, Jung Whan Song, Joo Heon Yoon |
1Department of Otolaryngology, College of Medicine, Ajou University, Suwon, Korea.
2Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
3Department of Otorhinolaryngology and Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea. jhyoon@yumc.yonsei.ac.kr
4Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Seoul, Korea. |
| 비용을 동반한 만성 부비동염의 세균학적 배양과 항생제 감수성 |
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김현준, 이경원, 유종범, 송정환, 윤주헌 |
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아주대학교 의과대학 이비인후과학교실,1 연세대학교 의과대학 진단검사의학교실,2 이비인후과학교실,4 기도 점액 연구소,4 한림대학교 의과대학 이비인후과학교실3 |
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| Abstract |
Background and Objectives
Microbiologic data in chronic sinusitis with nasal polyps, which is the foundation of proper antibiotic treatment, is insufficient due to problems with sampling and culture technique. Therefore, the objective of this study is to identify the causative agents in chronic sinusitis with nasal polyps based on culture results in adults and children and the relationship between the results of the middle meatus and maxillary sinus.
Materials and Method
Samples were obtained with middle meatus swabs and endoscopically guided maxillary sinus aspirations and then transferred to a microbiology laboratory using different media for aerobic and anaerobic cultures.
Results
Eighty one samples were studied. Sixty six from the middle meatus and sixty four from the maxillary sinus bacterial isolates were recovered. The most frequently isolated aerobic organisms were the Staphylococcus, Haemophilus influenza and Streptococcus while those of the anaerobic organisms in adults were the Prevotella and Peptostreptococcus. No anaerobic microorganisms were isolated in the children. Concordance rates of aerobic bacteria were 75.4% among adults and 90.0% among children. That of anaerobic bacteria was 83.6% among adults and 100% among children between the middle meatal swab and the maxillary sinus aspiration.
Conclusion
Authors recommend amoxacillin/clavulanate, cephalosporins and macrolide as the first-line medical treatment. In cases where there are no improvement of symptoms, cultures should be taken from the middle meatus, followed by appropriate selection of second-line antibiotics according to the sensitivity test results. |
| Key Words:
Antimicrobial susceptibility;Sinusitis;Bacteria;Culture;Susceptibility;Children;Adult |
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