Journal of Rhinology 2009;16(2):95-98.
Published online November 30, 2009.
Alteration of Olfactory Function in Chronic Viral Hepatitis Patients
Hyun Joo Park, Seung Sin Lee, Sung Wan Byun, Jung Ho Bae
Department of Otorhinolaryngology, School of Medicine, Ewha Womans University, Mokdong Hospital, Seoul, Korea. jhent@ewha.ac.kr
만성 바이러스성 간염 환자에서 후각 기능의 변화
박현주, 이승신, 변성완, 배정호
이화여자대학교 의학전문대학원 목동병원 이비인후과학교실
Abstract
Background and Objectives
Alterations of olfactory function among patients with cirrhosis of the liver, acute viral hepatitis or alcoholic liver disease have been reported. The goal of this study is to evaluate the alteration of olfactory function among chronic viral hepatitis patients.
MATERIALS AND METHODS
The study group consisted of 21 patients with chronic active viral hepatitis and 32 normal subjects. Between December 2006 and January 2008, olfactory function among the study groups was evaluated using the Connecticut Chemosensory Clinical Research Center and the Cross Cultural Smell Identification Test. Then, correlations between the olfactory function test scores and serological data were analyzed.
Results
Hepatitis patients had significantly lower smell identification test scores. Only serum total bilirubin level had negative correlation with smell identification test scores.
Conclusion
Chronic viral hepatitis appears to influence olfactory function.
Key Words: Liver diseases;Hepatitis;Olfaction




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