Journal of Rhinology 2009;16(2):105-109.
Published online November 30, 2009.
The Study of pH in Nasal Secretion in Normal and Chronic Rhinosinusitis
Ho Jin Lee, Jong Cheol Choi, Jung Hee Yoon, Nam Sik Joe, Chan Ho Kim, Jong Yeup Kim
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Konyang University, Daejeon, Korea.
정상인과 만성 비부비동염 환자에서 비즙의 pH측정과 비교
이호진, 최종철, 윤정희, 조남식, 김찬호, 김종엽
건양대학교 의과대학 이비인후과학교실
Background and Objectives
Nasal mucosal pH have a direct effect on the alteration of the physio-chemical characteristics of the nasal mucosa. Previous studies have reported the normal mucosal pH to be within the range of 5.3-7.0, mucosal pH with sinusitis to be within 6.8-7.6 and mucosal pH with rhinitis to be within 7.2-8.3. However, no consideration was paid to the conditions that influence the pH and there were no measured pH value by different methods. This study was therefore designed with the latest trend method in pH measurement with the purpose of evaluating pH in nasal secretion and creating an objective parameter for a beneficial manifestation of mucosa.
Materials and Method
S: We measured the pH values from 30 normal control group (group 1), 30 patients with chronic sinusitis (group 2), and 30 patients with allergic rhinitis (group 3). Nasal secretion was obtained through filter paper absorption method and, using a micro pH electrode with pH meter, pH was measured in nasal secretion.
pH in nasal secretion in this study was higher than the nasal mucosal pH from previously reported studies. pH values in nasal secretion showed a significant difference between three groups (group 1:7.86, group2:8.06, group 3:8.24) in this study (p<0.01).
The measurement of pH in nasal secretion seems to be a useful parameter for monitoring and assessing the state of nasal mucosa. And we recommend this study as a method for obtaining an objective parameter for pH measurement in nasal cavity.
Key Words: pH;Nasal secretion;Chronic rhinosinusitis;Nasal mucosa

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