A Case of Fibrous Dysplasia Simultaneously Involving the Sphenoid Sinus and the Clivus

Kim, Na Hyun; Kim, Si Hong; Kim, Kyung Rok; Kim, Kyung Su

Case Report

Journal of Rhinology 2009;16(2):162-165.
Published online November 30, 2009.

A Case of Fibrous Dysplasia Simultaneously Involving the Sphenoid Sinus and the Clivus

Na Hyun Kim, Si Hong Kim, Kyung Rok Kim, Kyung Su Kim

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea. ydrhinol@yuhs.ac

접형동과 사대를 동시에 침범한 섬유성 골이형성증

김나현, 김시홍, 김경록, 김경수

연세대학교 의과대학 이비인후과학교실

Abstract

Fibrous dysplasia is an uncommon benign bone disorder in which normal medullary bone is replaced by fibrotic and osseous tissue. Limited involvement of the sphenoid sinus or the clivus is extremely unusual. Here, we present a case of fibrous dysplasia in a 46-year-old female that involved the sphenoid sinus and the clivus simultaneously. Imaging modalities demonstrated an expansile lesion filling the entire left sphenoid sinus, extending to the clivus. Biopsy specimen was obtained by endoscopic sphenoid sinusotomy, and it showed extensive spindle-shaped fibroblastic cells with irregularly shaped trabeculae of woven bone which was compatible with fibrous dysplasia. After 6-month follow-up, the patient displayed no evidence of recurrence.

Key Words: Fibrous dysplasia;Sphenoid sinus;Clivus