Two Cases of Diffuse Large B-cell Lymphoma of Sinonasal Tract

Jang, Seong Yun; Jung, Jinsei; Kang, Ju Wan; Yoon, Joo Heon

Case Report

Journal of Rhinology 2009;16(2):169-172.
Published online November 30, 2009.

Two Cases of Diffuse Large B-cell Lymphoma of Sinonasal Tract

Seong Yun Jang, Jinsei Jung, Ju Wan Kang, Joo Heon Yoon

¹Department of Otorhinolaryngology, Wallace Memorial Babtist Hospital, Busan, Korea.
²Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea. jhyoon@yuhs.ac

비, 부비동에 발생한 미만성 거대 B세포 림프종 2예

장성윤, 정진세, 강주완, 윤주헌

왈레스 기념 침례병원 이비인후과,¹ 연세대학교 의과대학 이비인후과학교실²

Abstract

Nasal lymphoma is an uncommon neoplasm in the sinonasal tract. The NK/T-cell type of lymphoma is more commonly found in Asian populations. However, B-cell lymphoma is more common in the western countries whereas it is rare in Asia. Recently, we experienced two cases of sinonasal B-cell lymphoma, which are rare cases in Korea, one in an advanced stage and one in an early stage. Both patients had no specific nasal symptoms or systemic B symptoms (fever, night sweat, weight loss). As our cases demonstrate, diagnosis of B cell lymphoma is often delayed in many cases because B-cell lymphoma does not show any specific symptoms. Thus, careful physical examination and biopsy under suspicion of malignancy are important for early diagnosis of nasal lymphoma.

Key Words: Nasal lymphoma;B-cell lymphoma;Sinonasal tract