| Otorhinolaryngologic Application of Stem Cells |
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Byung Ki Yoon, Dong Kyu Kim, Dae Woo Kim, Hong Ryul Jin |
1Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
2Department of Otorhinolaryngology-Head and Neck Surgery, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. doctorjin@daum.net |
| 줄기세포의 이비인후과적 적용 |
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윤병기, 김동규, 김대우, 진홍률 |
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한림대학교 의과대학 춘천성심병원 이비인후과학 교실1, 서울대학교 의과대학 보라매병원 이비인후과학 교실2 |
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| Abstract |
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Stem cells can be isolated from almost any tissue in the body and are capable of proliferating in an undifferentiated manner and, under appropriate inductive conditions, differentiating into multiple cell lineages. Numerous studies are being conducted around the world using stem cells in various medical fields, including otorhinolaryngology. This review provides a brief overview of the method used for human stem cell isolation, the current status of clinical applications in the field of otorhinolaryngology as well as in general medicine, and lastly, suggests the future potential of stem cells in otorhinolaryngologic surgery. Within the field of otorhinolaryngology, stem cells have been clinically used or studied in four main areas: bony framework reconstruction, soft tissue augmentation, cartilage repair and wound healing. Outcomes of stem cell application appear promising; however, further basic research and clinical studies with longer follow-up periods are needed to develop safe and successful clinical applications. |
| Key Words:
Stem Cell;Otorhinolaryngology;Tissue Engineering |
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