Journal of Rhinology 2014;21(2):126-131.
Published online November 30, 2014.
A Case of Skull Base Plasmacytoma Presenting with Unilateral Cheek Paresthesia in Patient with Multiple Myeloma
Ki Ha Hwang, Chang Mook Park, Hyun Soo Cho, Jung Soo Kim
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. sookim@knu.ac.kr
다발성 골수종 환자에서 일측 안면부 감각저하를 동반한 두개저형질세포종 1례
황기하, 박창묵, 조현수, 김정수
경북대학교 의학전문대학원 이비인후과학교실
Abstract
Plasmacytoma is a monoclonal neoplastic proliferation of plasma cells derived from bone marrow. Plasmacytoma of the skull base is very rare. Recently, the authors experienced a case of a 50-year-old woman with a tumor like lesion originating from the right sphenoid bone. The patient presented with a 3-month history of right facial pain and paresthesia. She had been diagnosed and treated with multiple myeloma for more than 5 years, although she was in complete remission until recently. Imaging studies including contrast CT scan and MRI, showed a huge, enhanced and irregular shaped lesion in the sphenoid bone along with skull base destruction and intracranial invasion. The patient underwent transnasal endoscopic biopsy under local anesthesia. The pathology was consistent with a plasma cell tumor and it was confirmed as a solitary plasmacytoma of the bone of the skull base. We report this rare case along with a literature review.
Key Words: Plasmacytoma;Skull Base;Sphenoid Bone;Multiple Myeloma




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